…The MN and P blood types were discovered using the serum obtained by injecting human red blood cells into rabbits, but later (around 1937, published in 1940), Landsteiner, in collaboration with AS Wiener (1907-76), discovered the Rh factor using the same method. That is, when rabbits were immunized with red blood cells from rhesus monkeys, antibodies were produced that agglutinated the red blood cells of not only rhesus monkeys but also about 85% of Caucasians, and this reaction was independent of the ABO, MN, and P blood types. … From [Exchange transfusion]…This treatment prevents the development of jaundice, or kernicterus, in the brain tissue of newborns and protects them from cerebral palsy. This treatment for newborns was first performed by Wiener AS in 1944, but for adults it was already performed by Robertson OH in 1921 to treat burns. Today, it is used in newborns for blood incompatibility, as well as in adults for fulminant hepatitis (a specific type of hepatitis that develops rapidly and becomes severe), hemorrhagic diseases, and poisoning. … *Some of the terminology that mentions "Wiener, AS" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…MNとP血液型はヒトの赤血球をウサギに注射して得られた血清を使って発見されたが,その後(1937ころ。発表は1940)ラントシュタイナーはウィーナーA.S.Wiener(1907‐76)と共同で,これと同じ手法でRh因子を発見した。すなわち,アカゲザルrhesus monkeyの赤血球でウサギを免疫したところ,アカゲザルだけでなく白人の約85%の血球を凝集させる抗体が産生され,その反応はABO,MNおよびP血液型とは無関係であった。… 【交換輸血】より…この治療により,新生児の脳組織における黄疸,すなわち核黄疸の発生を防止し,脳性麻痺から守ることができる。この新生児への治療は1944年にウィーナーA.S.Wienerが初めて行ったものであるが,成人に対しては,やけどの治療のために,すでに1921年にロバートソンO.H.Robertsonが行っていた。今日では,新生児の血液不適合のほか,成人の劇症肝炎(急激に発症して重篤になる特殊な肝炎)や出血性疾患,毒物の中毒のときに行われている。… ※「Wiener,A.S.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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