Interstitial fluid

Japanese: 間質液 - かんしつえき
Interstitial fluid

A type of liquid component (body fluid) contained in living organisms, it refers to the extracellular fluid remaining after excluding plasma, lymph, and cerebrospinal fluid. Also called tissue fluid, it fills the spaces between cells in each tissue. In humans, interstitial fluid accounts for about 15% of body weight. Interstitial fluid contains various ions, but its composition is almost the same as that of lymph. It also has the same composition as plasma, except that it does not contain plasma proteins.

In body tissues other than the liver, lungs, etc., interstitial fluid is in contact with blood through the blood vessel walls and with intracellular fluid through cell membranes, and helps exchange of substances between blood and intracellular fluid. Interstitial fluid is produced when part of the plasma permeates through the capillaries, and after moistening the tissues, it returns to the blood vessels, but some enters the lymphatic vessels.

[Hidenobu Mashima]

[Reference] | Lymph

Source: Shogakukan Encyclopedia Nipponica About Encyclopedia Nipponica Information | Legend

Japanese:

生体に含まれる液体成分(体液)の一種で、細胞外液のうち、血漿(けっしょう)、リンパ、脳脊髄(せきずい)液を除いた残りをさす。組織液ともよばれ、各組織において細胞の間隙(かんげき)を満たしている。間質液は、ヒトの場合は体重の約15%を占める。間質液には、各種イオンが含まれるが、その組成はリンパ液のそれにほぼ等しい。また、血漿タンパクを含まないこと以外は、血漿の組成とも等しい。

 肝、肺等以外の体組織においては、間質液は血管壁を介して血液と、また、細胞膜を介して細胞内液と接しており、血液と細胞内液との物質交換を助けている。間質液は、毛細血管において血漿の一部が透過されて生じ、組織を潤したあと、ふたたび血管に戻るが、一部はリンパ管に入る。

[真島英信]

[参照項目] | リンパ

出典 小学館 日本大百科全書(ニッポニカ)日本大百科全書(ニッポニカ)について 情報 | 凡例

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