Warm ischemia time

Japanese: 温阻血時間 - おんそけつじかん
Warm ischemia time

...Apart from kidneys, which have two organs, organs that only have one can only be obtained from cadavers. The time from when blood flow stops to when the organ is transplanted and blood flow resumes is called the ischemic time. If ischemic time occurs at body temperature, cells die because they are not supplied with oxygen or nutrients, even though their metabolism is still occurring. This time is called the warm ischemic time, which is set at 0 minutes for the heart and liver and 30 minutes for the kidneys and lungs, and organs must be cooled quickly to suppress cell metabolism. If the organ is removed from a brain-dead patient with the heart still beating, it can be taken out without any damage, and the warm ischemic time can be shortened.

*Some of the terminology that refers to "warm ischemic time" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…臓器が二つある腎臓は別として,一つしかない臓器は,死体から得る以外にない。臓器の血流が止まってから臓器を移植して血流が再開するまでの時間を阻血時間というが,とくに体温の状態で阻血がおこると,細胞の代謝が行われているにもかかわらず,酸素や栄養が補給されないため細胞が死滅するので,この時間を〈温阻血時間〉と呼び,心臓や肝臓では0分,腎臓や肺では30分とし,早く臓器を冷やして細胞の代謝を抑えるようにしなければならない。心臓が動いている脳死の状態で摘出すれば,障害のないまま取り出すことができ,温阻血時間も短くできる。…

※「温阻血時間」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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