Dissecting aneurysm of aorta

Japanese: 解離性大動脈瘤 - かいりせいだいどうみゃくりゅう（英語表記）dissecting aneurysm of aorta

Aortic aneurysm is a disease in which the tunica media, which is the middle layer of the three-layered aortic wall, undergoes necrosis and is divided into an inner layer and an outer layer, and blood flows into the gap, forming a lump. In most cases, blood returns to the aorta, but it can rupture and cause massive bleeding. Attacks begin suddenly with severe pain and symptoms such as vomiting. Possible causes include genetic fragility of vascular tissue and arteriosclerotic lesions, and the disease is thought to develop when combined with sudden changes in blood pressure and blood flow. The mortality rate at the time of acute onset is high, with a report of a 20% mortality rate within 24 hours. Treatment includes the administration of antihypertensive drugs as well as angioplasty and artificial blood vessel replacement surgery.

Source: Encyclopaedia Britannica Concise Encyclopedia About Encyclopaedia Britannica Concise Encyclopedia Information

Japanese:

3層になっている大動脈の血管壁のうち，まんなかにある中膜に壊死などが生じて内層と外層に分れ，その間に血液が流入して瘤 (こぶ) 状になる病気。大半の場合，血液は大動脈に戻るが，破裂して大出血を起すこともある。発作は激痛を伴って急激に始り，嘔吐などの症状がある。原因としては血管組織の遺伝的な脆弱性や動脈硬化性病変などが考えられており，血圧や血流の急激な変化が加わって発症するとみられる。急性発症時の死亡率は高く，24時間で 20%との報告がある。治療には降圧剤の投与のほか，血管形成手術や人工血管の置換手術などが行われる。

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