...This property has been applied to experiments on gene transfer and gene recombination by conjugation and introduction, and furthermore, it has become possible to transfer genes between different species through genetically modified plasmids, leading to the development of genetic engineering, including gene cloning. However, such experiments always carry the risk of producing microorganisms that are harmful to humans and living organisms in general (biohazards). DNA recombination experiments in genetic engineering require safety regarding the plasmids used and the hosts into which they are introduced, and the basic experimental guidelines are to use hosts with low survival capabilities in the natural environment and plasmids that have no conjugation capabilities and cannot be transmitted to other species. ... *Some of the terminology that mentions "biohazard" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…この性質は接合や導入による遺伝子転移,遺伝子の組換えの実験に応用され,さらに,遺伝子を組み換えたプラスミドを介して,異なる生物種間で遺伝子の転移ができるようになり,遺伝子クローニングをはじめとする遺伝子工学への発展を導いた。しかし,このような実験には,人間や生物一般に有害な微生物を生みだす危険(バイオハザードbiohazard)がつねにある。遺伝子工学のDNA組換え実験には,用いるプラスミドと導入される宿主に関して安全性が求められており,自然環境下での生存能力が低い宿主と,接合能力がなく他の生物種に伝播(でんぱ)されないプラスミドを使うことが基本的な実験指針になっている。… ※「biohazard」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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