Lugol's solution

Japanese: ルゴール液 - るごーるえき

This refers to iodine-potassium iodide solution, which is a highly concentrated iodine solution made by adding potassium iodide to iodine to make it soluble in water. It was named after the French physician Jean Georg Antoine Lugol (1786-1851), who first used it. There are the following types of Lugol's solution:

[Fumiji Koho]

Lugol's solution for internal use

It is made by adding 33 grams of iodine, 66 grams of potassium iodide, and purified water to make 1,000 milliliters, and is taken orally for conditions such as goiter.

[Fumiji Koho]

Compound iodine-glycerin

It is an improved version of Lugol's solution, also known as Seifert's solution. The formula and manufacturing method is to dissolve 12 grams of iodine and 24 grams of potassium iodide in approximately 25 milliliters of purified water, add 900 milliliters of glycerin, then add 45 milliliters of peppermint water, 5 milliliters of liquid phenol, and purified water to make a total of 1,000 milliliters, and mix well. It is a reddish-brown viscous liquid that is often used as a liniment for pharyngitis and tonsillitis in otolaryngology for the purpose of sterilization and disinfection. It does not hurt as it does not contain alcohol, but it dries slowly.

[Fumiji Koho]

Dental Iodine Glycerin

Lugol's solution used in dentistry is made by adding purified water to 100 milliliters of iodine, 8 grams of potassium iodide, 1 gram of zinc sulfate, and 35 milliliters of glycerin. It is used to disinfect dentin and root canals, and for gingivitis.

[Fumiji Koho]

Lugol's solution for bacterial staining

It is made by dissolving 1 gram of iodine and 2 grams of potassium iodide in 300 milliliters of purified water, and is used as a weak acid mordant for Gram staining.

[Fumiji Koho]

[Reference] | Gram staining method | Iodine

Source: Shogakukan Encyclopedia Nipponica About Encyclopedia Nipponica Information | Legend

Japanese:

ヨウ素・ヨウ化カリウム液をいい、ヨウ素にヨウ化カリウムを加えて水に溶けるようにした高濃度のヨウ素溶液である。フランスの医師ルゴールJean Georg Antoine Lugol（1786―1851）が初めて用いたところから名づけられた。ルゴール液には次のようなものがある。

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内服用ルゴール液

ヨウ素33グラム、ヨウ化カリウム66グラムに精製水を加えて1000ミリリットルとしたもので、甲状腺腫(せんしゅ)などに内服する。

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複方ヨード・グリセリン

ルゴール液の改良処方で、ザイフェルト液ともよばれる。処方および製法は、ヨウ素12グラム、ヨウ化カリウム24グラムを精製水約25ミリリットルに溶かし、これにグリセリン900ミリリットルを加えたのち、ハッカ水45ミリリットル、液状フェノール5ミリリットルおよび精製水を加えて全量を1000ミリリットルとし、よく混和する。赤褐色の粘稠(ねんちゅう)性の液で、耳鼻咽喉(いんこう)科では、殺菌消毒の目的で咽頭炎や扁桃(へんとう)炎などに塗布剤としてよく用いられている。アルコールを含まないので痛くないが、乾きが遅い。

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