It is also called the Warburg-Dickens pathway, the phosphogluconate pathway, or the hexose phosphate cycle (Figure). It is a metabolic pathway that starts from glucose and is broadly divided into the following two reaction systems: (1) The irreversible production of pentose phosphate by oxidative decarboxylation of glucose-6-phosphate. This reaction also produces NADPH, the reduced form of NADP + . (2) A reversible process in which various phosphate esters of trioses, tetroses, pentoses, hexoses, and heptoses are mutually converted. Source: Heibonsha World Encyclopedia, 2nd Edition Information |
ワールブルク=ディケンズ経路,ホスホグルコン酸経路,ヘキソースリン酸回路とも呼ばれる(図)。グルコースを出発点とする代謝経路の一つで,次の二つの反応系に大別される。(1)グルコース‐6‐リン酸の酸化的脱炭酸によるペントースリン酸の不可逆的生成。この反応でNADP+の還元型NADPHも生成する。(2)各種トリオース,テトロース,ペントース,ヘキソース,ヘプトースのリン酸エステルが相互に変換する可逆的過程。
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