Also known as the laws of the heart. A law concerning the self-regulation of the heart's pumping function, discovered by British physiologist Ernest Henry Starling (1866-1927) and his collaborator Frank O. Frank using a heart-lung specimen from 1900 to 1914. For this reason, it is also known as the Frank-Starling law. The first of Starling's laws states that when the amount of blood flowing into the heart from the vena cava (venous return) increases, the end-diastolic volume of the ventricle increases, but the heart adapts to maintain its pumping function by increasing the stroke volume. Source: Heibonsha World Encyclopedia, 2nd Edition Information |
心臓の法則ともいう。心臓のポンプ機能の自己調節性に関する法則で,イギリスの生理学者スターリングErnest Henry Starling(1866‐1927)および彼の共同研究者フランクO.Frankが1900‐14年に心肺標本を使用して,これを発見した。このためフランク=スターリングの法則ともいう。スターリングの法則の第1は,大静脈から心臓への流入血液量(静脈環流)が増大すると,心室の拡張期末容積は増大するが,心臓は一回拍出量を増加させることによって,そのポンプ機能を維持するように適応しているというもの。
出典 株式会社平凡社世界大百科事典 第2版について 情報 |
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