This is a method to detect cold agglutinin, an antibody that agglutinates blood cells and bacteria in cold conditions below 37℃. In cases of mycoplasma pneumonia, infectious mononucleosis, viral pneumonia, etc., the cold agglutinin level in serum increases, so this method is used to diagnose these conditions. For this reason, mycoplasma pneumonia is also called cold agglutination test positive pneumonia. In severe cases of mycoplasma pneumonia, 75-90% of cases are positive, but even in healthy people, some cold agglutinin is found, so other tests must be used in combination to make a definitive diagnosis. Source: Encyclopaedia Britannica Concise Encyclopedia About Encyclopaedia Britannica Concise Encyclopedia Information |
37℃以下の寒冷状態で血球や細菌を凝集させる抗体である「寒冷凝集素」 cold agglutininを検出する方法。マイコプラズマ肺炎,伝染性単核症,ウイルス性肺炎などの場合,血清中の寒冷凝集素の値が上昇するので,その診断に利用される。このためマイコプラズマ肺炎のことを寒冷凝集反応陽性肺炎ともいう。重症のマイコプラズマ肺炎の場合には 75~90%が陽性になるが,健康人の場合でも多少の寒冷凝集素は認められるので,確定診断にはその他の検査法を併用する必要がある。
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