Ubiquinone

Japanese: ubiquinone
Ubiquinone

…Terpenes important to animals include the fat-soluble vitamins A, E, and K. In addition, a series of compounds called ubiquinone or coenzyme Q (CoQ) consists of a quinone ring and a long isoprene side chain, and are present in mitochondria as components of the electron transport system. Polyprenols are derivatives with a primary alcohol group at the end, and one of them, dolichol, plays an important role as a phosphate ester in the biosynthesis of cell walls and glycoproteins. …

From [Coenzyme]

… Pyridoxal phosphate bound to glycogen phosphorylase has a completely different role as a coenzyme, and the phosphate group is understood to be involved in the decomposition of glycogen molecules as a substrate. (7) Others Heme, a derivative of porphyrin in which iron is coordinated to tetrapyrrole, is a coenzyme for various oxidoreductases, and ubiquinone, or coenzyme Q (abbreviated as CoQ), is also important in the electron transport system. Many coenzymes play important roles in biological reactions, such as tetrahydrofolic acid in the transfer of C1 units such as formyl groups, cobamide coenzyme as vitamin B12 in lipid and nucleic acid metabolism involving intramolecular transfer of H, C, and other molecules (anemia is a well-known deficiency symptom), ATP in phosphoryl group transfer, and S -adenosylmethionine in methyl group transfer. …

*Some of the terminology that mentions "ubiquinone" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…動物にとって重要なテルペンとして脂溶性ビタミンA,E,Kがある。さらにユビキノンubiquinoneまたはコエンザイムQ(CoQ)と呼ばれる一連の化合物はキノン環と長いイソプレン側鎖からなり,ミトコンドリアに存在して,電子伝達系の構成成分となっている。ポリプレノールは末端に一級アルコール基をもつ誘導体で,その一つドリコールdolicholはリン酸エステルとして細胞壁や糖タンパク質の生合成過程で重要な役割を担っている。…

【補酵素】より

… なおグリコーゲンホスホリラーゼに結合しているピリドキサルリン酸は,補酵素としての役割が上記とまったく異なり,リン酸基が基質としてのグリコーゲン分子の分解に関与すると理解されている。(7)その他 テトラピロールに鉄が配位したポルフィリンの誘導体としてのヘムは各種酸化還元酵素の補酵素として,またユビキノンubiquinone,すなわち補酵素Q(CoQと略記)も電子伝達系で重要。テトラヒドロ葉酸はホルミル基などのC1ユニットの転移に,ビタミンB12としてのコバミド補酵素cobamide coenzymeはH,Cその他の分子内転移をめぐる脂質,核酸代謝に(欠乏症としては貧血が有名),ATPはリン酸基転移に,S‐アデノシルメチオニンはメチル基転移にというぐあいに,多くの補酵素が生体反応で重要な役割をになっている。…

※「ubiquinone」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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