Prolactin-inhibiting factor

Japanese: prolactin-inhibiting factor(英語表記)prolactininhibitingfactor
Prolactin-inhibiting factor

…Synthetic LH-RH is widely used in gonadotropin reserve tests. (6)PIF is an abbreviation for prolactin inhibiting factor, and is also called prolactin secretion inhibitor. It is widely believed that its main component is dopamine, but this has not been confirmed. …

From [Prolactin]

…The extramammary effects of prolactin include promoting adrenal androgen secretion, and in animals it has a luteal maintenance effect and an effect on water-electrolyte metabolism, but these effects are unclear in humans. Prolactin secretion is regulated by both the hypothalamic hormones prolactin-releasing factor (PRF) and prolactin-inhibiting factor (PIF), with PIF dominating the control. In addition to the physiological milk secretion associated with pregnancy and childbirth, galactorrhea can also be observed, and in many cases is caused by excessive secretion of prolactin. …

*Some of the terminology that mentions "prolactin-inhibiting factor" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…合成LH‐RHは,ゴナドトロピン予備能検査に広く用いられている。(6)PIF prolactin inhibiting factorの略で,プロラクチン分泌抑制因子ともいう。その本体はドーパミンであるという考え方が有力であるが,確定はされていない。…

【プロラクチン】より

…プロラクチンの乳腺外作用としては副腎アンドロゲン分泌促進作用があり,また動物では黄体維持作用,水電解質代謝に及ぼす作用があるが,ヒトでは明らかでない。プロラクチンの分泌は視床下部ホルモンのプロラクチン分泌促進因子prolactin‐releasing factor(PRF)とプロラクチン分泌抑制因子prolactin‐inhibiting factor(PIF)の両者によって調節されており,PIFの支配が優位である。妊娠,分娩に伴う生理的な乳汁分泌以外にも乳汁漏出を認めることがあり,多くはプロラクチンの分泌過剰が原因である。…

※「prolactin-inhibiting factor」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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