…The green rings caused by copper deposition on the cornea are called Kayser-Fleischer rings, and are a characteristic finding of this disease. The main cause of increased copper deposition in tissues is believed to be a low level of ceruloplasmin (a protein that binds and transports copper) in the patient's serum. Treatment involves long-term administration of D-penicillamine, which binds copper and increases its excretion in the feces. … *Some of the terminology that mentions "ceruloplasmin" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…角膜に生じた銅沈着による緑色の輪はカイザー=フライシャー輪Kayser‐Fleischer ringと呼ばれ,この病気に特徴的な所見である。組織中への銅沈着の増加は,患者血清中のセルロプラスミンceruloplasmin(銅と結合し,運搬するタンパク質)が少ないことが最大の原因とされている。治療は,銅と結合しその糞便中への排出を増加させる作用を有するD‐ペニシラミンの長期投与による。… ※「ceruloplasmin」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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