A factor that induces mutations in living organisms, and when it is a substance it is called a mutagen or simply a mutagen. These mutagens often also have teratogenic and carcinogenic properties. Mutations occur naturally at a certain frequency, but under the action of certain factors, mutations can be induced at a higher frequency than the natural frequency of mutations. These factors are called mutagens, and the main examples include temperature changes, radiation, and chemicals. Mutagens often act on the DNA that makes up the genes in cells, changing the order and combination of base sequences. Source: Heibonsha World Encyclopedia, 2nd Edition Information |
生物に突然変異を誘発する要因をいい,それが物質の場合は突然変異原物質あるいは単に変異原物質という。これら突然変異原は,催奇形性や癌原性をももつことが多い。突然変異は自然界でも一定の頻度で発生しているが,ある要因の作用下では,自然の突然変異発現の頻度よりも高頻度で突然変異が誘発される。この要因が突然変異原で,おもなものとして,温度変化,放射線,化学物質などがあげられる。突然変異原は多くの場合,細胞中の遺伝子を構成するDNAに作用し,塩基配列の順序や組合せを変異させる。
出典 株式会社平凡社世界大百科事典 第2版について 情報 |
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