…A proteolytic enzyme that is active in the acidic region and is secreted into gastric juice from the chief cells of the gastric mucosa. Under the acidic conditions of gastric juice, the inactive precursor pepsinogen is autocatalytically degraded in part to become pepsin. Depending on the degree of degradation, it is heterogeneous and not a single substance. … *Some of the terminology explanations that mention "pepsinogen" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…胃粘膜の主細胞から胃液中に分泌される,酸性領域で活性をもつタンパク質分解酵素。不活性の前駆物質ペプシノーゲンpepsinogenが,胃液の酸性条件下で,自己触媒的に分子の一部が分解され活性化してペプシンとなる。分解の程度によるが,不均一で単一物質ではない。… ※「pepsinogen」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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