Sideroblastic anemia

Japanese: sideroblastic anemia(英語表記)sideroblasticanemia
Sideroblastic anemia

…Anemia can be cured by injection of vitamin B12 , so in modern times it is considered to be a benign anemia and the term pernicious anemia is not appropriate. Sideroblastic anemiaHemoglobin is formed when a protein called globin binds to a substance called heme, which is made of iron and protoporphyrin. Sideroblastic anemia is caused by a disorder in the synthesis of protoporphyrin in erythroblasts, and because there is an excess of iron in the cells, when iron staining is performed, ring-shaped sideroblasts with iron granules surrounding the nuclei of erythroblasts are increased in the bone marrow, and hypochromic microcytic erythrocytes appear in the bloodstream. …

*Some of the terminology that mentions "sideroblastic anemia" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…ビタミンB12の注射で貧血は治るので,現代ではむしろ良性の貧血であり悪性貧血という名称は適切でない。 鉄芽球性貧血sideroblastic anemiaヘモグロビンは,ヘムという鉄とプロトポルフィリンからなる物質に,グロビンとよばれるタンパク質が結合してできる。鉄芽球性貧血はプロトポルフィリンの赤芽球内での生合成の障害によって生じ,鉄が細胞内に過剰にあるため,鉄染色をすると赤芽球の核をとり囲んで鉄顆粒のある環状鉄芽球が骨髄内に増加し,低色素性小球性赤血球が流血中に出現する。…

※「sideroblastic anemia」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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