...To date, more than 20 types are known, and the E and F types, which have uterine contraction and vasodilatory effects, have been put to practical use. S. Bergström, who determined the (chemical formula) structure, B. Samuelsson, who discovered the arachidonic acid cascade and thromboxane A 2 (platelet aggregation), and J. Vane, who discovered PGI 2 (vasodilatory and blood coagulation inhibition) and the relationship between aspirin action and prostaglandins, were awarded the Nobel Prize in Physiology or Medicine in 1982. Prostaglandins are metabolized quickly, mainly in the lungs. ... *Some of the terminology that mentions "Bergström, S." is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…現在までに20種類以上が知られ,子宮収縮作用,血管拡張作用のあるE系,F系が実用化されている。(化学式)構造を決定したベルイストロームS.Bergström,アラキドン酸カスケード,トロンボキサンA2(血小板凝集)を発見したサムエルソンB.Samuelsson,PGI2(血管拡張,血液凝固抑制)を発見しアスピリン作用とプロスタグランジンとの関係を発見したベーンJ.Vaneの3人は82年,ノーベル生理学・医学賞を受賞した。プロスタグランジンは肺を中心に代謝は速い。… ※「Bergström,S.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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