...When the chemical nature of hormones was unknown and it was difficult to separate and purify them, dried powders and crude extracts of various endocrine organs were used. Dried thyroid powder (containing the hormone thyroxine) is the only organ preparation still officially approved for use in Japan, and is obtained by rapidly drying the thyroid glands of livestock at temperatures below 50°C. It was not so long ago that dried acetone powder of the posterior pituitary gland was used clinically as a uterotonic agent. *Some of the terminology that refers to "dried thyroid" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…ホルモンの化学的実体が不明で,分離精製が困難であった時代には,いろいろな内分泌器官の乾燥粉末,粗エキスが用いられた。乾燥甲状腺末(含まれるホルモンはチロキシン)は,現在も日本で正式に使用が認められている唯一の臓器製剤であり,家畜甲状腺を50℃以下で急速乾燥して得られる。脳下垂体後葉のアセトン乾燥粉末が子宮収縮剤として臨床上使われていたのも,それほど昔のことではない。… ※「乾燥甲状腺」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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