Interstitial cell stimulating hormone

Japanese: 間質細胞刺激ホルモン - かんしつさいぼうしげきほるもん

…They are also called gonadotropic hormones. In vertebrates, they include two hormones secreted from the anterior pituitary gland: follicle-stimulating hormone (abbreviated as FSH) and luteinizing hormone (abbreviated as LH) or interstitial cell-stimulating hormone (abbreviated as ICSH), and chorionic gonadotropin (abbreviated as CG, but abbreviated as hCG in humans), secreted from the placenta. Both are glycoproteins, and in humans, FSH has a molecular weight of about 35,000, while LH and hCG have a molecular weight of about 30,000. …

From [Testosterone]

...Its action promotes the development of the penis, scrotum, prostate, and seminal vesicles, as well as the growth of muscles and bones, the development of body hair and facial hair, and the change in voice, which are secondary sexual characteristics in men. The Leydig cells in the interstitium of the testis synthesize and secrete testosterone from cholesterol when stimulated by luteinizing hormone (LH, also known as interstitial cell-stimulating hormone) secreted from the anterior pituitary gland. Conversely, testosterone acts on the diencephalon (hypothalamus) of the brain to suppress the secretion of gonadotropin-releasing factor, thereby suppressing the secretion of pituitary gonadotropins. ...

*Some of the terminology that mentions "stromal cell-stimulating hormone" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…生殖腺(性腺)刺激ホルモンともいう。脊椎動物では，脳下垂体前葉から分泌される卵胞(濾胞)刺激ホルモンfollicle‐stimulating hormone(FSHと略す)と黄体形成ホルモンluteinizing hormone(LHと略す)または間質細胞刺激ホルモンinterstitial cell‐stimulating hormone(ICSHと略す)の2種のホルモンと，胎盤から分泌される絨毛（じゆうもう）(膜)性ゴナドトロピンchorionic gonadotropin(CGと略すが，ヒトの場合はhCGと略す)が含まれる。ともに糖タンパク質で，ヒトのFSHは分子量約3万5000,LH,hCGは約3万である。…

【テストステロン】より

…その作用は，陰茎，陰囊，前立腺，精囊などの発達を促し，筋肉や骨の成長，体毛やひげなどの発生，声変りなど男子の二次性徴を促進する。　睾丸間質のライディヒ細胞は，脳下垂体前葉から分泌される黄体形成ホルモンLH(間質細胞刺激ホルモンとも呼ばれる)の刺激により，コレステロールからテストステロンを生合成して分泌する。逆にテストステロンは脳の間脳(視床下部)に作用してゴナドトロピン放出因子の分泌を抑制し，脳下垂体ゴナドトロピン分泌を抑制する。…

※「間質細胞刺激ホルモン」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典第２版について | 情報

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