This enzyme is secreted from the pancreas and small intestinal mucosa and acts to cleave amino acids at the C-terminus (carboxyl terminus) of proteins and peptides. It is secreted from the pancreas as procarboxypeptidase, which is activated by trypsin or enterokinase in the duodenum to become this enzyme. There are two types: enzyme A (enzyme number 3.4.2.1), which acts on neutral and acidic amino acids, and enzyme B (enzyme number 3.4.2.2), which acts specifically on lysine and arginine. In addition, there are metalloenzymes in animals and microorganisms that act selectively on certain amino acids. Source: Encyclopaedia Britannica Concise Encyclopedia About Encyclopaedia Britannica Concise Encyclopedia Information |
膵臓や小腸粘膜から分泌される酵素で,蛋白質やペプチドのC末端 (カルボキシル末端) のアミノ酸を切り離す働きをする。膵臓からプロカルボキシペプチダーゼの形で分泌され,それが十二指腸でトリプシンまたはエンテロキナーゼによって活性化されて本酵素となる。中性および酸性アミノ酸に働く酵素A (酵素番号 3.4.2.1) と,リジンやアルギンに特異的に働く酵素B (酵素番号 3.4.2.2) の2つの型がある。そのほか,あるアミノ酸に選択的に作用する金属酵素が動物や微生物にある。
出典 ブリタニカ国際大百科事典 小項目事典ブリタニカ国際大百科事典 小項目事典について 情報 |
<<: Carboxyl group - Carboxyl group
A hero of Greek mythology. Son of Apollo and Epika...
The process of ionizing gaseous atoms, acceleratin...
...Many metal peroxoacid salts, such as peroxochr...
Yamada-ryu Sokyo performer and composer. Grandson...
…Fruits can be classified based on the shape of t...
…It has a high sprouting ability and forms second...
...Originally, it was derived from Pollock, who w...
…Calderón's followers included Moreto and Roj...
…Other proteins that are involved in the polymeri...
Year of death: March 11, 1724 (April 4, 1724) Year...
It is the name of a region and a province in the ...
...Its founder was Hugo Gernsback (1884-1967), an...
A species of the Orthoptera family Phoridae, or a ...
Founded in March 1874 (Meiji 7) as the official j...
The 77th Emperor (reigned 1155-58). His given nam...