…It is characterized by the degeneration and loss of nerve cells in the cerebellum, brain stem, and basal ganglia, as well as spongy changes in tissue and argyrophilic structures called kuru spots. In 1964, DC Gajdusek (1923-, winner of the Nobel Prize in Physiology or Medicine in 1976) and his colleagues successfully induced a similar encephalopathy in a chimpanzee by injecting a brain emulsion from a kuru patient into the brain of the chimpanzee 18 to 30 months later, demonstrating that the disease is transmissible. … *Some of the terminology explanations that mention "Gaijusek, DC" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…小脳,脳幹,大脳基底核などの神経細胞の変性・脱落とともに組織の海綿状変化,クールー斑と呼ばれる嗜銀性構造物を特徴とする。1964年D.C.ガイジュセック(1923‐ 。1976年ノーベル生理・医学賞受賞)らは,クールー患者の脳乳剤をチンパンジーの脳内に接種し,18~30ヵ月後に同様な脳症を発症させることに成功し,伝播性であることを示した。… ※「ガイジュセック,D.C.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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