Ectopic ACTH syndrome

Japanese: 異所性ACTH症候群 - いしょせいえーしーてぃーえっちしょうこうぐん
Ectopic ACTH syndrome

…Adrenocorticotropic hormone ( ACTH There are various types of cortisol, including excessive secretion of ACTH from the adrenal cortex (Cushing's disease, first reported by the American H. Cushing (1869-1939)), excessive secretion of cortisol from a tumor in the adrenal cortex, and increased secretion of cortisol from the adrenal glands as a result of secretion of ACTH from a tumor outside the pituitary gland (ectopic ACTH syndrome).
[Symptoms/Diagnosis]
Symptoms include moon face, central obesity (obesity of the trunk only), striae, high blood pressure, osteoporosis, menstrual irregularities, hirsutism, hypokalemia, and impaired glucose tolerance.

*Some of the terms that refer to "ectopic ACTH syndrome" are listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…脳下垂体腺腫から副腎皮質刺激ホルモン(ACTH)が過剰に分泌される結果,副腎皮質からのコルチゾール分泌が増加するもの(クッシング病。アメリカのH.カッシング(1869‐1939)が初めて報告),副腎皮質に発生した腫瘍からコルチゾールが過剰に分泌されるもの,脳下垂体以外の腫瘍からACTHが分泌される結果,副腎からのコルチゾール分泌が増加するもの(異所性ACTH症候群)などの病型がある。
[症状・診断]
 満月様顔貌,中心性肥満(体幹のみの肥満),皮膚線条,高血圧,骨粗鬆(そしよう)症,月経異常,多毛,低カリウム血症,耐糖能低下などの症状を呈する。…

※「異所性ACTH症候群」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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