Amyloid degeneration

Japanese: アミロイド変性 - あみろいどへんせい

...Analysis of the amino acid sequence has revealed that there are two main types of amyloid proteins: a protein with a molecular weight of 5,000 to 25,000 belonging to the immunoglobulin light chain, and amyloid A protein with a molecular weight of about 8,500. However, the existence of several other amyloid proteins has been revealed. When amyloid deposits in a part of the body or in tissues throughout the body, it is pathologically called amyloid degeneration, and the disease that is the main form of this is called amyloidosis. The cause of amyloidosis is unknown, and there are secondary forms that occur in association with various chronic diseases, primary forms that occur without any preceding disease, forms that occur in conjunction with multiple myeloma, localized forms, hereditary familial forms, and senile forms. ...

From [denaturation]

...When granular material appears in the cytoplasm and cells or tissues appear cloudy, it is called cloudy swelling, which is also a type of protein degeneration. In amyloidosis, amyloid accumulates in the interstitium outside the cells, which is called amyloid degeneration. The deposition of pigments in cells or tissues is also called pigmentary degeneration. ...

*Some of the terminology that refers to "amyloid degeneration" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…そのアミノ酸配列の分析によって，タンパク質は免疫グロブリンのL鎖に属する分子量5000～2万5000のタンパク質と，分子量約8500のアミロイドAタンパク質との2種類が主要タンパク質とされているが，これら以外に数種のアミロイドタンパク質の存在が明らかにされている。アミロイドが身体の一部に，あるいは全身の組織に沈着した場合，病理形態学的にアミロイド変性と呼び，これを本態とする疾患をアミロイドージスamyloidosisという。アミロイドージスの原因は不明で，種々の慢性疾患に伴っておこる続発性のもの，先行する疾患なしにおこる原発性のもの，多発性骨髄腫に合併するもの，限局性のもの，遺伝性家族性のもの，老人性のものなどがある。…