...Since strain C does not have either of these functions, the DNA of the phage grown in strain C is not modified and is eliminated in strain B cells. It was revealed by W. Arber and others (1968) that the modification function is an enzyme that recognizes and methylates specific DNA sequences, and the restriction function is an endonuclease that specifically cuts unmethylated DNA. The restriction enzyme discovered in strain B was named Eco B after the scientific name of Escherichia coli . ... *Some of the terminology that mentions "Arber, W." is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…C株はこのどちらの機能ももたないので,C株で増殖したファージのDNAは修飾を受けておらず,B株細胞内で排除されてしまう。この修飾機能を担っているのはDNAの特異的配列を認識してメチル化する酵素であり,制限機能を担っているのはメチル化されていないDNAを特異的に切断するエンドヌクレアーゼであることが,アーバーW.Arberなどによって明らかにされた(1968)。B株で発見された制限酵素は大腸菌の学名Escherichia coliにちなみEco Bと命名された。… ※「アーバー,W.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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