...Drugs discovered in Japan and used clinically include Toju Hata's carzinophilin (1954), mitomycin (1956), Hamao Umezawa's bleomycin (1966), peplomycin (1977), aclacinomycin A (brand name Aclarubicin, 1977), Sueo Tateoka's chromomycin A 3 (1955), and Naosuke Ishida's neocarzinostatin (1965). Bleomycin and mitomycin in particular are widely used overseas. Drugs discovered overseas that are used for treatment include actinomycin D, daunorubicin (brand name Daunomycin), and doxorubicin (brand name Adriamycin). In general, anticancer drugs are not effective against visceral cancers such as stomach cancer and lung cancer, but doxorubicin is said to be effective against various visceral cancers. ... *Some of the terminology explanations that mention "Adriasin" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…日本で発見され臨床的に用いられているものに,秦藤樹のカルチノフィリン(1954),マイトマイシン(1956),梅沢浜夫のブレオマイシン(1966),ペプロマイシン(1977),アクラシノマイシンA(商品名アクラルビシン,1977),立岡末雄のクロモマイシンA3(1955),石田名香雄のネオカルチノスタチン(1965)があり,とくにブレオマイシン,マイトマイシンは外国でもよく用いられている。外国で発見されたもので治療に用いられているものに,アクチノマイシンD,ダウノルビシン(商品名ダウノマイシン),ドキソルビシン(商品名アドリアシン)がある。一般に,胃癌,肺癌などの内臓癌には制癌剤が効きにくいが,ドキソルビシンは各種内臓癌に効くといわれている。… ※「アドリアシン」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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