…During World War II, he joined the resistance organization under German occupation. In 1945, he joined the Pasteur Institute, where he again worked under André Michael Lwoff (1902-94) on the production of β-galactosidase in E. coli. In 1951, he found that the enzyme was induced in the presence of an inducer, independent of metabolism. In 1959, together with Arthur Beck Pardee (1921- ) and François Jacob (1920- ), he performed a genetic analysis of the induction of this enzyme in E. coli (the pajama experiment), and based on these results, in 1961, together with Jacob, he proposed the operon theory. … *Some of the terminology that mentions "Lwoff, AM" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…第2次世界大戦中はドイツ占領下の抵抗組織に参加する。45年パスツール研究所に入り,ルウォフAndré Michael Lwoff(1902‐94)のところで再び大腸菌のβ‐ガラクトシダーゼ生成の研究にとり組み,51年酵素は誘導物質の存在により,代謝とは無関係に誘導されることを見いだした。59年にはパーディーArthur Beck Pardee(1921‐ ),ジャコブFrançois Jacob(1920‐ )とこの大腸菌の酵素誘導の遺伝的解析を行い(パジャマ実験),その結果などから61年ジャコブとともにオペロン説を提出した。… ※「Lwoff,A.M.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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