...However, when the ventilation function of the lungs deteriorates due to respiratory disease or a decrease in the function of the respiratory center, the partial pressure of carbon dioxide in the blood increases and the pH decreases (this is called respiratory acidosis). On the other hand, in cases of uremia, diabetic ketosis, diarrhea, and shock, excessive acid production, loss of base, or decreased acid excretion occurs, resulting in a decrease in bicarbonate ions in the blood and a decrease in pH (this is called metabolic acidosis). As acidosis progresses, it can cause disorders of the central nervous system and circulatory system, such as impaired consciousness, arrhythmia, and decreased blood pressure, and can lead to death. ... *Some of the terminology that mentions "metabolic acidosis" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…ところが,呼吸器の病気や呼吸中枢の機能低下により,肺の換気機能が悪くなると,血液の炭酸ガス分圧が上昇し,pHは低下する(これを呼吸性アシドーシスrespiratory acidosisという)。一方,尿毒症,糖尿病性ケトーシス,下痢,ショックなどでは,酸の産生の過剰,塩基の喪失,または酸の排出の低下が起こり,血液の重炭酸イオンが低下し,pHは低下する(これを代謝性アシドーシスmetabolic acidosisという)。アシドーシスが進行すると,意識障害,不整脈,血圧の低下など,中枢神経系,循環系の障害が起こり,死に至る。… ※「metabolic acidosis」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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