Opsonin

Japanese: opsonin
Opsonin

…In the process of recognition, bacteria are first ingested by neutrophils after being enveloped by humoral factors in serum. These humoral factors are called opsonins and consist of serum globulins and complements. When a neutrophil comes into contact with an opsonized bacterium, a part of the neutrophil's cytoplasm extends as if it is extending its hands, surrounding the bacterium with two arms just like embracing a ball, and finally the two arms fuse together to completely enclose the bacterium within the cell. …

From [Macrophage]

…In vertebrates, there are receptors for the Fc end of antibodies and complement, and they efficiently ingest objects that are bound to these. In this way, substances that aid in phagocytosis are collectively called opsonins. Macrophages play an important role as trimming cells for morphogenesis in embryos (fetuses) and as processing cells for degenerated or mutated cells (including cancer cells) in adults, and are essential cells for the survival of animals. …

*Some of the terminology that mentions "opsonin" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…認識する過程では,細菌が血清中の液性因子によって包まれて初めて好中球にとり込まれる。この液性因子をオプソニンopsoninと呼び,血清グロブリンや補体からできている。好中球はこのオプソニンで包まれた細菌に接すると,好中球の細胞質の一部が手を出すように伸展し,ちょうど2本の腕でボールを抱くように細菌をとり囲み,ついに2本の腕は一つに癒合して完全に細胞の中に封じ込んでしまう。…

【マクロファージ】より

…脊椎動物では,抗体のFc末端や補体に対する受容体があり,それらの結合した物体を能率よく捕食する。このように,食作用を助ける物質はオプソニンopsoninと総称されている。 マクロファージは胚(胎児)における形態形成のトリミング細胞として,成体においても変性あるいは変異細胞(癌細胞を含む)の処理細胞としても重要な働きを示し,動物の生存に不可欠の細胞である。…

※「opsonin」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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