…These immature leukemia leukocytes often show atypical characteristics in terms of cell size, nuclear type, the proportion of the nucleus in the cell, the color of the cytoplasm, and the shape and size of the granules compared to cells of the same maturation stage present in normal bone marrow. For example, Auer bodies, which can be seen in acute myeloid leukemia, are granules present in normal myeloid leukocytes that have been deformed into rod-like shapes, and when these bodies are seen, it is easy to tell that they are myeloid leukemia leukocytes. In addition, a major characteristic of adult T-lymphocytic leukemia, a type of acute lymphocytic leukemia, is that the nuclear shape of the leukemia leukocytes is severely deformed, becoming clover-shaped or glove-like. … *Some of the terminology explanations that mention "Auer body" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…これらの幼若な白血病の白血球は,正常骨髄に存在する同じ成熟段階の細胞と比べると,細胞の大きさ,核の型,核が細胞中で占める割合,細胞質の色調,顆粒の形や大きさ,などの点で異型性を示すことが少なくない。たとえば,急性骨髄性白血病に認められることのあるアウエル小体Auer bodyは,正常骨髄系白血球に存在する顆粒が杆状に変型したものであり,この小体を認める場合には,それが骨髄性白血病の白血球であることを容易に知ることができる。また,急性リンパ性白血病の中の成人型Tリンパ球性白血病では,白血病の白血球の核の型がクローバー状になったり,手袋様になるなど強い変型を伴うことを大きな特徴としている。… ※「Auer body」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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