Takayasu disease

Japanese: 高安病 - たかやすびょう

Also known as pulseless disease or aortitis syndrome. A disease in which the pulse cannot be felt in the hands or neck arteries in young women. Designated an incurable disease. It is an obstructive lesion that begins in the aorta in the chest or abdomen and extends to the carotid arteries, subclavian arteries, and renal arteries. Blockage of the carotid arteries in particular can cause poor blood circulation to the brain, leading to fainting episodes and decreased vision. Peculiar changes can be seen in the fundus of the eyes. The cause is unknown. Corticosteroids are effective in the early stages, and if the carotid artery is blocked, reconstructive surgery for the blocked blood vessels is attempted, but treatment is generally difficult.

Source : Heibonsha Encyclopedia About MyPedia Information

Japanese:

脈無病，大動脈炎症候群ともいう。若い女性で手や頸(けい)部の動脈の脈拍が触知できない病気。難病に指定。胸部や腹部の大動脈から起こり，頸動脈，鎖骨下動脈，腎動脈に及ぶ閉塞(へいそく)性病変で，特に頸動脈の閉塞により脳血行が不良となり，失神発作，視力低下をきたす。眼底に特異な変化がみられる。原因は未確定。初期には副腎皮質ホルモン剤が有効で，頸動脈に閉塞をきたした場合は，閉塞血管の再建手術が試みられるが，一般に治療困難。

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