...By the way, there are many enzymes whose substrate saturation curves are not hyperbolic, but are S-shaped (sigmoidal) or rectangular, as shown in Figure 6. This phenomenon is often seen in allosteric enzymes and is called cooperative effects. The properties of such curves are expressed by a parameter called the Hill coefficient (abbreviated as n ). The Hill coefficient can be calculated by drawing the graph in Figure 8. ... *Some of the terminology explanations that refer to the "cooperative effect" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…ところで,酵素の中には基質飽和曲線が双曲線性でなく,図6のようにS字性(シグモイド性)や矩形に近い形を与えるものも少なくない。この現象はアロステリック酵素によく見られるもので,協同効果cooperative effectsと呼ばれるが,このような曲線の性質をヒル係数Hill coefficient(nと略記)というパラメーターで表す。ヒル係数は図8の作図によって求められる。… ※「協同効果」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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