...Abnormalities in the small bile ducts within the liver are called intrahepatic cholestasis, and include drug-induced liver injury and a disease caused by an autoimmune disorder called primary biliary cirrhosis. In contrast, when the lumen of the bile duct is obstructed by cholelithiasis, bile duct cancer, or pancreatic head cancer, extrahepatic obstructive jaundice occurs. If intrahepatic cholestasis continues for a long period of time, it will become biliary cirrhosis. ... *Some of the terminology that refers to "extrahepatic obstructive jaundice" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…肝臓内の細い胆管の異常によるものを肝内胆汁鬱滞と呼び,薬剤性肝障害や原発性胆汁性肝硬変と呼ばれる自己免疫異常による疾患が含まれる。それに対し,胆石症,胆管癌,膵頭部癌により胆道内腔が閉塞されると,肝外閉塞性黄疸が生じる。長期間,肝臓内の胆汁鬱滞が続くと,胆汁性肝硬変となる。… ※「肝外閉塞性黄疸」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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