…Many histocompatibility antigens have been found, but the ones that cause the strongest rejection reactions are called major histocompatibility antigens, and their presence has been confirmed in many higher animals. Representative examples are human HLA antigens (discovered as human leukocyte antigens in 1958) and mouse H-2 antigens. The higher the match rate of major histocompatibility antigens in bone marrow or kidney transplants, the higher the survival rate of the transplanted organ. … *Some of the terminology that mentions "H-2 antigen" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…多くの組織適合抗原が見いだされているが,最も強い拒絶反応をもたらすものを主要組織適合抗原といい,高等動物で広くその存在が確認されている。ヒトのHLA抗原(1958年にヒト白血球抗原として発見された)およびマウスのH‐2抗原がその代表的なものである。骨髄あるいは腎臓などの移植に際して主要組織適合抗原の一致率が高いほど,移植臓器の生着率は高くなる。… ※「H-2抗原」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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