...Blood for transfusion is made by adding the anticoagulant ACD or CPD solution (both consisting of citric acid, sodium citrate, and glucose, with the latter containing sodium hydrogen phosphate NaH 2 PO 4 ) to the collected blood and storing it at 4 to 6 degrees Celsius, mainly to suppress the metabolism of red blood cells. Stored blood includes whole blood and concentrated red blood cells, but currently concentrated red blood cells refers to red blood cell MAP, which is made by removing the buffy coat (a component containing white blood cells and platelets) and most of the plasma from whole blood and adding a new storage solution MAP solution (mannitol, adenine, phosphate). Therefore, it is the name of blood for transfusion up to 21 days after collection. ... From [Blood Transfusion]… The blood used for component transfusion is prepared by centrifuging whole blood immediately after collection. In other words, the blood collected in a plastic bag is separated into red blood cell concentrate and platelet rich plasma (abbreviated as PRP) using the anticoagulant ACD (acid-citrate-dextrose). The platelet rich plasma is further centrifuged to separate it into buffy coat (constituents of platelets and white blood cells) and the supernatant platelet poor plasma (abbreviated as PPP). This platelet poor plasma, a transparent plasma that does not contain blood cell components such as platelets, is frozen at -20°C or below to become fresh frozen plasma. … *Some of the terminology that refers to "ACD (blood anticoagulant)" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…輸血用血液は,採取した血液に抗凝固剤であるACD液またはCPD液(いずれもクエン酸,クエン酸ナトリウム,ブドウ糖からなり,後者にはリン酸水素ナトリウムNaH2PO4が加わる)を加え,主として赤血球の代謝を抑えるために4~6℃で保存されるが,保存血には全血と濃厚赤血球が含まれるが,現在濃厚赤血球は全血よりバフィコート(白血球と血小板を含む成分),血漿のほとんどを除き,新しい保存液MAP液(マニトール,アデニン,フォスフェート)を加えた赤血球MAPを指す。したがって採血後21日目までのこれらの輸血用血液の名称である。… 【輸血】より… この成分輸血に用いられる血液は,採血直後の全血を遠心分離によって調製する。すなわち抗凝固剤ACD(acid‐citrate‐dextrose)を用いて,プラスチックバッグに採血した血液を赤血球濃厚液と多血小板血漿platelet rich plasma(PRPと略記)に分離する。多血小板血漿はさらに遠心分離してバフィコート(血小板と白血球の成分)と上清の乏血小板血漿platelet poor plasma(PPPと略記)に分離し,この乏血小板血漿,血小板など血球成分を含まない透明な血漿を-20℃以下で凍結したものが,新鮮凍結血漿である。… ※「ACD(血液抗凝固剤)」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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