Waterhouse-Friederichsen syndrome

Japanese: ウォーターハウス=フリーデリクセン症候群 - うぉーたーはうすふりーでりくせんしょうこうぐん

...After the onset of symptoms similar to upper respiratory tract infection, the first symptoms of sepsis are erythema 1-3 mm in diameter that appears all over the body, which rapidly disappears within 2-3 days, followed by meningeal irritation and cranial nerve paralysis. Sometimes there is a fulminant type in which only sepsis symptoms occur and death occurs within 24 hours, but when adrenal hemorrhage is also present, this is called Waterhouse-Friderichsen syndrome and is often fatal. Haemophilus influenzae meningitis is common in children up to about 2 years of age, while pneumococcal meningitis is common in those under 1 year of age and over 50 years of age. ...

From [Epidemic meningitis]

...Rash and sensory hypersensitivity are also often observed. When the patient shows severe systemic symptoms, with severe bleeding in the skin and adrenal glands and a shocking progression, it is called Waterhouse-Friderichsen syndrome. Appropriate chemotherapy has reduced the mortality rate and aftereffects such as visual impairment and hearing loss.

*Some of the terminology that refers to "Waterhouse-Friederichsen Syndrome" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…上気道感染様症状の発症後，まず敗血症の症状として全身に直径1～3mmの紅斑が出現，2～3日で急速に消退し，ついで髄膜刺激症状や脳神経麻痺が出現する。ときに敗血症症状のみで24時間以内に死亡する電撃型があり，副腎出血を伴う場合はウォーターハウス=フリーデリクセン症候群Waterhouse‐Friderichsen syndromeと呼ばれ致命的なことが多い。インフルエンザ菌性髄膜炎は2歳くらいまでの幼児に多く，肺炎球菌性髄膜炎は1歳以下と50歳以上に多い。…

【流行性髄膜炎】より

…発疹，知覚神経過敏もしばしば認められる。激しい全身症状を示し，皮膚および副腎の出血が著しく，電撃的な経過をとるものをウォーターハウス=フリーデリクセン症候群Waterhouse‐Friderichsen syndromeという。適切な化学療法により死亡率は減少し，視力障害，聴力障害などの後遺症も減少した。…

※「ウォーターハウス=フリーデリクセン症候群」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典第２版について | 情報

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