…In 1947, he turned to biology, and instead of vitalistic meditation, he tried to understand the essence of life from the structure of its constituent molecules, and began researching protein structure at the Cavendish Laboratory. There, he met Watson, who had been a member of the American phage group, and became convinced of the importance of elucidating the structure of DNA (deoxyribonucleic acid). Based on the X-ray diffraction patterns of DNA obtained by X-ray crystallographers MHF Wilkins and RE Franklin, and the chemical analysis values of E. Chargaff, he and JD Watson proposed a model of the double helix molecular structure of DNA in 1953. This model convinced many researchers that genes are DNA, and it set the direction of molecular biology thereafter, leading to rapid development. … *Some of the terminology explanations that mention "Wilkins, MHF" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…1947年生物学に転じ,生命の本質を生気論的な瞑想を排して,構成分子の構造からとらえようと考え,キャベンディシュ研究所でタンパク質構造の研究を始めた。そこでアメリカのファージグループ出身のワトソンと出会い,DNA(デオキシリボ核酸)の構造解明の重要性を確信し,X線結晶学者M.H.F.ウィルキンズやR.E.フランクリンらの得たDNAのX線回折像およびE.シャルガフらの化学分析値などから,53年J.D.ワトソンとともにDNAの二重らせん分子構造モデルを提出する。このモデルは遺伝子がDNAであることを多くの研究者に確信させ,その後の分子生物学の方向を定め,急激な発展をもたらすことになった。… ※「ウィルキンズ,M.H.F.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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