...This refers to an antigen-antibody reaction in which tuberculin is an allergen, and is used as a test to determine whether or not one is infected with tuberculosis bacteria. Tuberculin was created in 1890 by R. Koch, the discoverer of tuberculosis bacteria, by concentrating the culture filtrate of tuberculosis bacteria. It did not initially become popular as a tuberculosis treatment as Koch had hoped, but Clemens F. von Pirquet (1874-1929), Charles Mantoux (1877-1947), and others established the tuberculin reaction as a method for diagnosing tuberculosis infection, and it has come to be widely used. *Some of the terminology that refers to "negative allergy" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…ツベルクリンをアレルゲンとした抗原抗体反応をいい,結核菌の感染を受けているかどうかを調べる検査法として利用される。ツベルクリンは1890年,結核菌の発見者であるR.コッホによって,結核菌の培養ろ(濾)液を濃縮してつくられた。当初コッホが期待したように結核治療薬としては普及しなかったが,ピルケーClemens F.von Pirquet(1874‐1929),マントゥーCharles Mantoux(1877‐1947)らにより,ツベルクリン反応は結核感染の診断法として確立され,広く用いられるようになった。… ※「陰性アレルギー」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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