...Acute poisoning due to large doses can cause coma, miosis, hypothermia, respiratory depression, and death due to respiratory arrest. For acute poisoning, especially respiratory depression, antagonists such as nalorphine and levallorphan are used. Caution is required when using these drugs in children, the elderly, and the debilitated, as they are particularly susceptible to respiratory depression. *Some of the terminology explanations that mention "levallorphan" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…大量摂取による急性中毒では,昏睡,縮瞳,体温降下,呼吸抑制から呼吸停止で死亡する。急性中毒,とくに呼吸抑制には,拮抗薬のナロルフィンnalorphine,レバロルファンlevallorphanなどを適用する。小児,老人,衰弱者にはとくに呼吸抑制作用が強く現れるため,使用には注意を要する。… ※「levallorphan」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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