physical dependence

...Psychic dependence is a state in which the person is unable to stop taking a drug as a result of repeated drug intake, and has a psychological desire to continue taking the drug. Physical dependence is a state in which various physical abnormalities, i.e. withdrawal symptoms, occur when the person stops taking the drug. This type of dependence, especially physical dependence, is accompanied by a so-called tolerance, in which the person must gradually increase the dosage of the drug to obtain the same medicinal effects as at the beginning.

*Some explanations of terms that mention "physical dependence" are listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

…薬物の反復摂取の結果として，その薬物の摂取がやめられなくなる状態で，精神的に薬物摂取の継続を渇望する状態を精神的依存psychic dependence，また，薬物摂取をやめると，種々の身体的異常，すなわち退薬症状(禁断症状)がでてくるような状態を身体的依存physical dependenceとよぶ。これらの依存，とくに身体的依存には，しだいに薬物の用量をふやさないと初めと同じ薬効が得られなくなる，いわゆる耐性toleranceが伴う。…

※「physical dependence」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典 第２版について | 情報