Radding, CM (English spelling) RaddingCM

Japanese: Radding,C.M.(英語表記)RaddingCM
Radding, CM (English spelling) RaddingCM


[Molecular mechanism of genetic recombination]
F. Meselson and J. Weigle used λ phage with visible mutations, and furthermore, took advantage of the ability to change DNA density using non-radioactive isotopes ( 13C for 12C , 15N for 14N ) to show that genetic recombination (in this case, intrachromosomal recombination) occurs through DNA breakage and recombination (1961). Based on these research results, Meselson and CM Radding proposed the currently most widely accepted molecular mechanism of intrachromosomal recombination (Figure 1) (1975). The Meselson and Radding model has attracted attention because it can provide a unified explanation not only for intrachromosomal recombination but also for gene conversion. …

*Some of the terminology that refers to "Radding, CM" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:


[遺伝的組換えの分子機構]
 メセルソンF.MeselsonとワイグルJ.Weigleは,目で見て区別できる変異をもつλファージを用い,さらに,非放射性同位体(12Cに対して13C,14Nに対して15N)によってDNAの密度を変えられることを利用して,遺伝的組換え(この場合は染色体内組換えに相当する)がDNAの切断と再結合によって起こることを示した(1961)。メセルソンとラディングC.M.Raddingはこの研究結果を基盤にして,現在のところ最も広く受け入れられている染色体内組換えの分子機構(図1)を提唱した(1975)。メセルソンとラディングの模式は,染色体内組換えだけでなく,遺伝子変換gene conversionをも統一的に説明できるので注目されている。…

※「Radding,C.M.」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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