Ethionamide

Japanese: ethionamide
Ethionamide

...For patients with smear-negative and no cavities, INH and RFP are used in combination from the beginning, for a treatment period of 6 to 9 months. If resistance develops to any of the antituberculosis drugs listed above or if side effects make them unusable, other drugs will be used instead. In terms of effectiveness and side effects, kanamycin (abbreviated as KM) and ethionamide (abbreviated as TH) are easy to use. Pyrazinamide (abbreviated as PZA) is highly regarded in Europe and the United States and is used for the first two months of short-term chemotherapy, but it is not often used in Japan due to its strong side effects. ...

*Some of the terminology that mentions "ethionamide" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…塗抹陰性で空洞のない患者では,初めからINHとRFPの2者併用で,治療期間は6~9ヵ月とする。上記の処方中の抗結核薬のいずれかに耐性が生じたり,副作用で使えないときには,その薬に代えて他の薬を用いることになるが,効果と副作用からみて用いやすいのはカナマイシンkanamycin(KMと略記),エチオナミドethionamide(THと略記)などである。ピラジナミドpyrazinamide(PZAと略記)は欧米では高く評価され,短期化学療法の当初2ヵ月くらい用いられているが,副作用が強く日本では多くは使われていない。…

※「ethionamide」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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