epitope

Japanese: epitope
epitope

... The functions of an antigen are not present in the entire antigen molecule, but are closely related to the chemical and three-dimensional structure of a specific portion of the antigen molecule. Such a portion is called a determinant or epitope, and in most cases, it has a molecular weight of 500 to 1000 and is about 4 x 2 x 1 nm in size, and consists of 5 to 8 amino acids for protein antigens and 5 to 6 monosaccharides for polysaccharide antigens.
[Antigen specificity and its basis]
Antibodies produced by the body in response to a particular antigen (or present in small amounts in normal animals) or sensitized lymphocytes react only with determinants specific to that antigen.

*Some of the terminology explanations that mention "epitope" are listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

… 抗原のこのような機能は抗原分子全体にあるのではなく,その限定された部位がもつ化学的・立体的構造との関連が深い。このような部分を決定群(基)またはエピトープepitopeと呼び,多くの場合,分子量500~1000で4×2×1nmくらいの大きさをもち,タンパク質抗原ではアミノ酸5~8個,多糖体抗原なら単糖5~6個くらいの大きさからなる。
[抗原特異性とその基盤]
 特定の抗原の免疫で生体がつくった(または正常動物が少量もつ)抗体または感作リンパ球は,その抗原に特有な決定群とのみ反応する。…

※「epitope」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

<<:  epitrochoid

>>:  Epitonium scalare (English spelling) Epitoniumscalare

Recommend

Álayabijñāna - Álayabijñāna

... Next, regarding the "non-self of all phe...

Iolite (English spelling)

Contains iron, aluminum, and magnesium Silicates E...

Vanda coerulea (English spelling)

…[Koichi Ejiri]. … *Some of the terminology that ...

Kawasaki Bank

…There are two types of conglomerates called the ...

Noro Kaiseki

A Southern painter of the late Edo period. His gi...

Funagoya [Hot Spring] - Funagoya

A hot spring in Chikugo City, Fukuoka Prefecture. ...

Hanabusaichou - Hanabusaichou

A painter of the early Edo period. The founder of...

international currency

…For example, a currency cannot be a base currenc...

Functional psychology

The concept of functional psychology generally re...

Cassandra

A woman in Greek mythology. Daughter of Troy's...

New born chick; baby chick

Newly hatched chicken chicks. Raising day-old chic...

Machine board - Kiban

…The Chinese character 'machine' original...

Endonucleases

Among the enzymes that break down nucleic acids, ...

Monument to the deceased - Chukonhi

〘 noun 〙 A monument commemorating those who died f...

Kei - Kei

[Kanji for personal names] [Sound] Kei (Kanji) E (...