Dysmyelinating disease

…However, among the conditions that cause only the myelin sheath to be damaged, there are two types: those in which the myelin sheath that was once normally formed is destroyed, and those in which the myelin sheath is not formed during neurogenesis due to congenital abnormalities. The former should truly be called a demyelinating disease, while the latter is a dysmyelinating disease, and must be distinguished from it. However, in reality, there are many cases in which the two processes coexist and it is difficult to distinguish between them. …

*Some of the terminology that refers to "dysmyelinating disease" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

…ただし，このような髄鞘のみの侵害を生ずるものには，一度正常に形成された髄鞘が破壊されるものと，先天性の異常のため，神経発生の途上において髄鞘が形成されないものとが区別される。前者は真に脱髄疾患と呼ばれるべきものであるが，後者は髄鞘形成不全dysmyelinating diseaseであり，これとは区別されなければならない。しかし実際には，これらの両方の過程が混在していて識別が困難な場合も少なくない。…

※「dysmyelinating disease」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典 第２版について | 情報