…These were later found to be RNA-type tumor viruses, but the Rous sarcoma virus was thoroughly studied in the 1970s, and provided a breakthrough in the current understanding of cancer genes. As RNA-type cancer viruses, the mouse mammary tumor virus was discovered by J. Bittner in the 1930s, the mouse leukemia virus by L. Gross, J. Molony, C. Friend, F. Rauscher, and others in the 1950s, and leukemia and malignant lymphoma viruses in guinea pigs, cats, cows, monkeys, and other animals have been discovered since the 1960s. It had long been suspected that human leukemia was also caused by viruses, but in the 1980s it was almost certain that adult T-cell leukemia was caused by an RNA-type virus (ATLV). … *Some of the terminology that mentions "Bittner, J." is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…これらはのちにRNA型の腫瘍ウイルスであることがわかったが,ラウス肉腫ウイルスは,70年代に徹底的に研究され,現在の癌遺伝子解明の突破口をつくった。 RNA型の癌ウイルスとしては,1930年代にビットナーJ.Bittnerがマウスによる乳癌ウイルス,50年代にグロスL.Gross,モロニーJ.Molony,フレンドC.Friend,ラウシャーF.Rauscherらによるマウス白血病ウイルスの発見,60年以降では,モルモット,ネコ,ウシ,サルなどの白血病や悪性リンパ腫ウイルスが発見されている。ヒトの白血病もウイルスが原因ではないかと長い間疑われていたが,80年代になって,成人型のT細胞白血病がRNA型ウイルス(ATLV)によることがほぼ明らかにされた。… ※「Bittner,J.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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