German-born American biochemist. He studied at the University of Königsberg, the University of Berlin, and the University of Munich, and obtained his MD from the University of Munich in 1924. After a fellowship at the University of Amsterdam, he returned to the University of Königsberg to study chemistry, became an assistant at the Kaiser Wilhelm Society Institute, and obtained his Ph.D. in 1927. He then conducted research at the University of Heidelberg, the Kaiser Wilhelm Society Institute, the Rockefeller Institute, and the Carlsberg Institute of Biological Research. In 1939, he traveled to the United States and conducted research at Cornell University, Harvard University, and other universities. He established the concept of high-energy phosphate bonds such as adenosine triphosphate (ATP), and in 1945 discovered coenzyme A (CoA), which plays an important role in metabolism such as the TCA cycle (citric acid cycle). For this achievement, he was awarded the Nobel Prize in Physiology or Medicine in 1953 together with H. Krebs. Source: Morikita Publishing "Chemical Dictionary (2nd Edition)" Information about the Chemical Dictionary 2nd Edition |
ドイツ生まれのアメリカの生化学者.ケーニヒスベルク大学,ベルリン大学,ミュンヘン大学で学び,1924年ミュンヘン大学でM.D.を取得.アムステルダム大学でのフェローシップの後,ケーニヒスベルク大学へ戻って化学を学び,カイザー・ウィルヘルム協会研究所の助手となり,1927年Ph.D.を取得.その後,ハイデルベルク大学,カイザー・ウィルヘルム協会研究所,ロックフェラー研究所,カールスベア生物学研究所で研究を行った.1939年アメリカに渡り,コーネル大学,ハーバード大学などで研究を行った.アデノシン三リン酸(ATP)などの高エネルギーリン酸結合の概念を確立し,1945年TCAサイクル(クエン酸回路)などの代謝において重要な役割を果たすコエンザイムA(CoA)を発見した.この功績により,1953年H. Krebs(クレブス)とともにノーベル生理学医学賞を受賞した. 出典 森北出版「化学辞典(第2版)」化学辞典 第2版について 情報 |
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