This is a carcinoma caused by the malignant transformation of trophoblastic cells, which are the nutrient cells of the placenta, and is also called malignant choriocarcinoma. It is a relatively rare disease among gynecological cancers. It occurs most frequently after a hydatidiform molar pregnancy, and is thought to occur in 5-10% of moles, but it can also occur after induced abortion, spontaneous abortion, or childbirth. It occurs when trophoblastic cells remaining in the body after pregnancy become cancerous, and usually occurs several months to several years after pregnancy (such choriocarcinoma is called gestational choriocarcinoma). In very rare cases, choriocarcinoma can develop as a teratoma in the ovaries or testes (in this case in boys) unrelated to pregnancy (this is called teratomatous choriocarcinoma). Source: Heibonsha World Encyclopedia, 2nd Edition Information |
胎盤の栄養細胞である絨毛細胞の悪性化によって発生する癌腫で,悪性絨毛上皮腫ともいわれる。婦人科癌のなかでは比較的まれな疾患である。胞状奇胎妊娠後に最も多く発生し,奇胎の5~10%に発生するとみられているが,人工妊娠中絶,自然流産,分娩後に発生する場合もある。妊娠後体内に遺残した絨毛細胞が癌化することで発生し,通常,妊娠後数ヵ月から数年を経て発症する(このような絨毛癌を妊娠性絨毛癌という)。ごくまれに,妊娠と関係なく卵巣や睾丸(この場合は男子に)に奇形腫として絨毛癌が発生することがある(これを奇形腫性絨毛癌という)。
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