An enzyme involved in the replication of viral RNA. RNA viruses have RNA as the genetic body within their particles. The reaction in which this RNA molecule is replicated within an infected cell is carried out by a mechanism different from that of the replication of the host genome (DNA replication), and involves enzymes (or enzyme subunits) derived from the viral genome. The RNA replication process occurs by different mechanisms depending on whether the genetic RNA is single-stranded (e.g., influenza virus) or double-stranded (reovirus), and the enzymes involved are called by various names (e.g., RNA-dependent RNA polymerase). Source: Heibonsha World Encyclopedia, 2nd Edition Information |
ウイルスRNAの複製に関与する酵素。RNAウイルスは遺伝子本体としてRNAを粒子内にもつ。このRNA分子が感染細胞内で複製される反応は,宿主ゲノムの複製(DNA複製)とは異なった機構で行われ,ウイルスゲノム由来の酵素(または酵素のサブユニット)が関与する。RNAの複製過程は,遺伝子RNAが一重鎖である場合(例えばインフルエンザウイルス),二重鎖である場合(レオウイルス)等の差異にもとづき,異なった機構で起こり,関与する酵素も種々の名称で呼ばれる(例えばRNA依存性RNAポリメラーゼ)。
出典 株式会社平凡社世界大百科事典 第2版について 情報 |
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