Antagonism

Japanese: 拮抗現象 - きっこうげんしょう
Antagonism

...The development of antibiotics and microbial products with antifungal, antiviral and new pharmacological properties is still ongoing, and antibiotics have made an enormous contribution to human health.
[History of the discovery of antibiotics]
Antagonism occurs when two types of microorganisms are cultured at the same time and the growth of one of them is inhibited. Research into antagonism is said to have begun with J. Tyndall (1876) and Pasteur (1877). In the 1900s, several people extracted substances that exhibited antagonism, and mycophenolic acid was reported, but no thought was given to using them as medicines.

*Some of the terminology explanations that refer to the "antagonism phenomenon" are listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…抗カビ,抗ウイルスまた新しい薬理作用をもった抗生物質,微生物生産物の開発も現在なお続けられ,抗生物質は人類の健康に貢献することきわめて大なるものがある。
【抗生物質の発見史】
 2種の微生物を同時に培養した場合に,一方の微生物の発育が阻止されることを拮抗現象antagonismと呼ぶが,拮抗現象の研究はJ.ティンダル(1876),パスツール(1877)に始まるといわれている。1900年に入って,何人もが拮抗現象を有する物質を抽出し,ミコフェノール酸などが報告されたが,医薬品としての利用は考えられていなかった。…

※「拮抗現象」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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