…Even if the number of constituent cells decreases, the size of the organ may not necessarily decrease because fat cells proliferate to fill the gaps. Also, brown atrophy is a condition in which brown granules are deposited in atrophied cells, and this is a state in which lipid peroxides in intracellular organelles and other substances accumulate as waste products. Atrophy is classified into physiological atrophy that occurs with aging (for example, atrophy of the thymus gland that occurs after puberty, atrophy of the reproductive organs that occurs after menopause, etc.) and pathological atrophy that occurs due to the addition of a pathological cause (for example, atrophy of the kidney due to chronic nephritis, atrophy of the liver due to fulminant hepatitis, etc.). … *Some of the terminology explanations that mention "brown atrophy" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…構成細胞の数がへっても,間隙を埋めるように脂肪細胞が増殖することによって,器官の大きさは必ずしも小さくならないこともある。また萎縮した細胞の中に褐色顆粒が沈着しているものを褐色萎縮というが,これは,細胞内小器官などの過酸化脂質が老廃産物としてたまった状態である。萎縮は,加齢(老化)とともに認められる生理的萎縮(たとえば,思春期以降におこる胸腺の萎縮,更年期以降におこる生殖器の萎縮など),病因が加わるためにおこる病的萎縮(たとえば,慢性腎炎による腎萎縮,劇症肝炎による肝萎縮など)に区別される。… ※「褐色萎縮」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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