Setsuro Ebashi - Setsuro Ebashi

Japanese: 江橋節郎 - えばしせつろう

Born: August 31, 1922, Tokyo
[Died] July 17, 2006. Pharmacologist, Okazaki, Aichi. Graduated from the Faculty of Medicine, Tokyo Imperial University in 1944. Served as a visiting researcher at the Rockefeller Institute in the United States in 1959, a professor at the Faculty of Medicine, University of Tokyo in the same year, a visiting professor at the University of California in 1963, a professor at the Faculty of Science, University of Tokyo in 1971, and a visiting professor at the Harvard Medical School in 1974. After retiring from the University of Tokyo in 1983, he served as a professor, director, and director of the National Institute for Physiological Sciences, Okazaki National Research Institute. In his research on the molecular physiological mechanism of muscle contraction, he discovered the role of calcium as a regulatory factor and elucidated its regulatory mechanism. He also revealed the existence of troponin as a calcium receptor protein and elucidated its role (1965). He further expanded his research field to other physiological processes involving calcium. He also discovered that creatine phosphokinase activity in the serum of patients with muscular dystrophy was extremely high, and based on this, he laid the foundation for a method to detect latent muscular dystrophy. He received the Imperial Prize of the Academy in 1972, the International Prize for Biology in 1999, and the Order of Culture in 1975.

Source: Encyclopaedia Britannica Concise Encyclopedia About Encyclopaedia Britannica Concise Encyclopedia Information

Japanese:

[生]1922.8.31. 東京
[没]2006.7.17. 愛知，岡崎
薬理学者。 1944年東京帝国大学医学部卒業。 1959年アメリカ合衆国のロックフェラー研究所客員研究員，同年東京大学医学部教授，1963年カリフォルニア大学客員教授，1971年東大理学部教授，1974年ハーバード大学医学部客員教授を歴任。 1983年に東大退官後，岡崎国立共同研究機構生理学研究所教授，同研究所長，同機構長を歴任。筋肉収縮の分子生理学的機構の研究で，調節因子としてのカルシウムの役割を発見し，その調節機構を明らかにした。また，カルシウムの受容体蛋白としてのトロポニンの存在を明らかにし，その役割も解明した (1965) 。さらにカルシウムが関与する他の生理過程に研究領域を広げた。また，筋ジストロフィー患者に血清中クレアチンホスフォキナーゼ活性が極めて高いことを発見，これをもとに潜在性筋ジストロフィー発見法の基礎を築いた。 1972年学士院賞恩賜賞，1999年国際生物学賞などを受賞，1975年文化勲章を受章。

出典　ブリタニカ国際大百科事典小項目事典ブリタニカ国際大百科事典小項目事典について　情報

<<: Ever Sharp - Ebar Sharp

>>: Evershed, J.