…When you touch your toe with a freshly extinguished match, you first feel a stabbing pain, followed by a delay of nearly one second, a longer-lasting burning pain. The peripheral nerve fibers that transmit the stabbing pain are thin, myelinated fibers with a diameter of 2-5 μm and a conduction speed of 12-30 m/s, called Aδ fibers, while the fibers that transmit the burning pain are even thinner, unmyelinated C fibers with a diameter of about 1 μm and a conduction speed of 0.5-2.0 m/s. The pain felt first is called first pain, and the pain felt later is called second pain. … From [Muscle pain]…In muscle tissue with a low pH, the activity of enzymes that destroy pain-inducing substances is suppressed, and ischemia prevents the outflow of pain-inducing substances, causing them to accumulate in the muscles, which also causes pain. Pain sensory fibers include large myelinated Aδ fibers that feel a sharp, stabbing pain, and small unmyelinated C fibers that feel a dull, dull pain. Under conditions of oxygen deficiency, the function of Aδ fibers is easily lost, and C fibers become dominant. … *Some of the terminology that refers to "Aδ fiber" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…消したばかりのマッチで足指に触れると,まず一瞬刺す痛みが起こり,それから1秒近く遅れて,より長く続くやけつく痛みが現れる。刺す痛みを伝える末梢神経繊維は,直径が2~5μmで,12~30m/sの伝導速度をもつ細い有髄の繊維でAδ繊維とよばれるが,やけつく痛みを伝えるのは,直径約1μmで0.5~2.0m/sの伝導速度をもつさらに細い無髄の神経繊維のC繊維である。そこで,初めに感ずる痛みを第1痛first pain,次いで遅れて感ずる痛みを第2痛second painともいう。… 【筋肉痛】より…またpHが低下している筋組織では発痛物質を破壊する酵素の活動は抑制されており,阻血によって発痛物質の流出が妨げられ筋肉内に蓄積されることも疼痛の発現の原因となる。痛覚神経繊維には,鋭い刺すような痛みを感じる大径有髄のAδ繊維と,鈍くてだるい痛みを感じる小径無髄のC繊維がある。酸素欠乏の条件下では,Aδ繊維の機能は容易に脱落して,C繊維優位の状態になる。… ※「Aδ 繊維」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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